Since the medication is injected locally into the joint there are hardly any side effects of using the hyaluronic acid injections except an allergic reaction and it is quite successful in treating pain due to degenerative arthritis. Rash and Hives have also been reported in some cases. However, swelling, pain and excess fluid were reported in 7% patients. Risks. Synvisc knee injections, also known as Hylan G-F 20, are one of the most common types of joint lubricant injections used for the treatment of knee arthritis. With SYNVISC being administered into the knee joint, and not into the blood, there is much less likely to be any side effects. On the other hand, because synvisc is directly injected into the joint, there are remote cases where patients complained of some swelling, discomfort, or pain in or around the knee. But the number of complaints was higher than expected. Source: RxLisT: Synvisc (Hylan G-F20) Mayo Clinic: Hylan Polymers A … Side Effects Euflexxa. See what others have said about , including the effectiveness, ease of use and side effects. Side Effects and Risks . Osteoarthritis is a type of arthritis in which the joints of the body degenerate and become painful and stiff. Hylan G-F 20 (Synvisc, Synvisc One) is a medication in injection form used to treat osteoarthritis of the knee. Comparing side effects Understanding the possibility of complications and adverse effects is important in making any treatment decision. Sanofi Genzyme’s Synvisc-One injections supplement natural synovial fluid in the knee. Knee Injections for Osteoarthritis: Types, Side Effects, and More SYNVISC is a viscosupplement injection that supplements the fluid in your knee to help lubricate and cushion the joint, and can provide up to six months of osteoarthritis knee pain relief with three injections. Get all related articles and updates directly to your inbox, subscribe to our mailing list. Is there anyone here who has had stem cell therapy for arthritic knees and I would like to know your outcome. This medication achieves its therapeutic effect through viscosupplementation, a process whereby the rheological and physiological states of the arthritic joint tissues are restored. Talk to your doctor about Synvisc if … By Email: medicalinformation@nuvopharm.com. they are great! With SYNVISC being administered into the knee joint, and not into the blood, there is much less likely to be any side effects. Sanofi Genzyme saw a spike in reported complications from its Synvisc-One knee injections in late 2017. Treatment (especially long-term treatment) with oral NSAIDs can result in stomach problems like bleeding, ulcer, and stomach upset, as well as high blood pressure and kidney problems. Swelling, pain, warmth would be possible side effects or the sign of something more serious. No single therapy works for everybody, and treatments vary in terms of risks, side effects, and how long their benefits last. The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. InflammationCBD.com. Tell your doctor if you experience any side effects after treatment with Synvisc-One. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Ferdowsi on synvisc 1 side effects: The short answer is no. It’s important to discuss all available options with your doctor. As you know supartz is a five injection series. Sometimes, this swelling is caused by the accumulation of fluid in the knee joint and requires draining. The types and frequencies of side effects were similar between the Synvisc-One and the saline control groups. 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